Abstract

ISSN

2249-7633

e ISSN

2249-7625

Publisher

Pharmacy Practice & Drug Research

IN VITRO EVALUATION OF IMMUNOMODULATORY ACTIVITY OF ETHANOLIC EXTRACT OF Catunaregum spinosa (thunb.) Tirveng ROOT BARK
Author / Afflication
KR. Anju

Assistant Professor, The Dale View College of Pharmacy and Research Centre, Trivandrum - 695 575, Kerala, India.
Keywords
Immunomodulatory , Preliminary Phytochemical screening ,T–cell proliferation ,
Abstract

Immunomodulators weaken or modulate the activity of the immune system. That, in turn, decreases the inflammatory response. In recent years, the immuno modulating properties of plants are being studied extensively with greater interest due to the growing awareness on immune system modulation and to achieve the desirable effects on disease prevention. Several plant remedies well-known in traditional medicine exert their anti-infective effects not only by directly affecting the pathogen, but also by stimulating natural and adaptive defense mechanisms of the host. Therefore plantremedies have become versatile means with improved immunotherapy. Catunaregum spinosa, is highly reputed ayurvedic medicinal tree commonly known as the Mainphal, Mindhal [2]. Literature reviews revealing the presence of triterpenoids in Catunaregum spinosa, and which helps in exhibiting immunomodulatory activity [3]. Preliminary phytochemical screening and T–cell proliferation assay was conducted to determine the immunomodulatory activity by in-vitro method

Volume / Issue / Year

7 , 2 , 2017

Starting Page No / Endling Page No

57 - 61