The aim of the study is to improve Health Related Quality of Life (HRQoL) , mental status and to decrease economic burden of patients with certain GI Disorders. The study being a randomized controlled trial where a total of 60 patients were enrolled from which the patients were divided into 2 groups namely Control group and Interventional group.The Control group received the usual care given by the Physician and the Interventional group received Structured Education by Pharmacist; which included education about disease, drugs and importance of adhering to the therapy regimen and Upon the second visit the patients were made to fill the Quality of Life and Psychiatric forms again. Then the 2 group scores were analyzed for pre test and post test by using SPSS software by using paired sample t-test. At the end of the study the outcomes were measured in both control and interventional group and it was found among both the groups that before patient education and after patient education there was statistically significant improvement in QOL,mental status and decrease in economic burden in the intervention group than that of control group.