Chronic diseases, including diabetes mellitus, require medication adherence as part of disease management. Patients with diabetes who abide poorly by medication may be less aware of overall therapeutic objectives, making them less likely to accomplish them. Objective: Aims of the study were to assess self-reported medication compliance, therapeutic goal knowledge (hemoglobin A1C [A1C], low density lipoprotein cholesterol [LDL-C] and blood pressure [BP]), and goal attainment in adults with diabetes. Methods: Adult patients with diabetes following up at a family medicine or internal medicine clinic were surveyed regarding medication adherence, therapeutic goals, and goal attainment. Prior to office visits, patients were asked to self-administer surveys. Additional data were collected from the electronic medical record. Analyses were conducted statistically. Results: There were 74 patients enrolled in the study. In terms of LDL-C, BP, and A1C, 14%, 34%, and 18% of survivors reported knowledge of therapeutic goals. LDL-C, blood pressure, and A1C goals were achieved by 46 percent, 37%, and 40% of patients, respectively. Interestingly, only 36% of patients not reaching their LDL-C goals had been prescribed a medication aimed at lowering cholesterol. Patients were nonadherent to 48% of their medications; forgetfulness (34%) and high cost (14%) were the most common reasons. There was a higher rate of adhesion among patients with an A1C goal (p = 0.025) than among those without an A1C goal. Conclusion: Although most patients failed to reach their goals and weren't aware of what they were trying to achieve, prescriptions were provided to treat these parameters. Members of a multidisciplinary team should revisit goal parameters frequently and communicate openly. Each visit should also include a discussion about medication adherence, since it is vital that practitioners discuss this with their patients