Pain is a common symptom encountered across all healthcare settings and it can significantly affect the quality of life of patients. In fact, analgesic medications have an important role in management of pain and it is commonly found prescribing in the inpatient department of hospitals. Assessment of the prescribing pattern of analgesics can helps us to know how the analgesics are prescribed and also whether these drugs are prescribed appropriately. METHODS: A prospective observational study was carried out using 216 patients admitted in the medicine ward of a tertiary care teaching hospital in Palakkad. Data collection forms which included demographic details, medical conditions, analgesic prescribed, route of administration, duration etc. RESULT: In the study most of the patients were aged between 61 and 70 years (27.7%), and around 61.1% of the study population were male. The most commonly prescribed drug class was found to be non-opioids (39.06%) and tramadol+ acetaminophen combination was the most prescribed analgesic (19.14%). Oral route of administration (79%) was most found, and majority of prescriptions (81.94%) were lasted for a duration of 6–10 days. Many patients received combination therapies ensuring a multimodal approach to pain management. CONCLUSION: This study suggests that prescribing pattern of analgesics was well structured, favoring non-opioid and short-term analgesic use. The regular monitoring of how these drugs is prescribed will help promote rational use