DOI:10.21276/ijppdr 

Abstract

ISSN

2249-7633

e ISSN

2249-7625

Publisher

Pharmacy Practice & Drug Research

A REVIEW ON SAFETY AND EFFICACY OF FIRST LINE ANTITUBERCULAR DRUGS
Author / Afflication
Pranathi Reddy R

Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor – 517127, Andhra Pradesh, India.
Bhavani D

Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor – 517127, Andhra Pradesh, India.
Deekshitha P

Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor – 517127, Andhra Pradesh, India.
Pravallika S

Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor – 517127, Andhra Pradesh, India.
Saravana kumar A

Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor – 517127, Andhra Pradesh, India.
Keywords
Drug induced convulsive seizures ,IGRAs test ,MTB ,DOTS regimen ,
Abstract

Tuberculosis is a bacterial infection caused by Mycobacterium tuberculosis, which spreads from infected person through salivary or cough droplets. In the present review it has been clearly described about the pharmacokinetic and pharmacodynamic study of first line anti-tubercular drugs like Isoniazid, Rifampicin, Pyrazinamide, Ethambutol and streptomycin. The biochemistry of the drugs were discussed along with their mechanism of action and its correlation with the structure of the active molecule of the drug. All the adverse drug reactions and various approaches for management of ADR’S have also been discussed with various comments of safety and efficacy.

Volume / Issue / Year

7 , 2 , 2017

Starting Page No / Endling Page No

62 - 67