ISSN
2249-7633
e ISSN
2249-7625
Publisher
Pharmacy Practice & Drug Research
ISOLATION AND CHARACTERIZATION OF AN ANTI ULCER COMPOUND FROM MURRYA KOENIGII (LINN.) SPRENG WETTST LEAVES
Author / Afflication
Prasanta Kumar Mitra
Department of Medical Biotechnology, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.
Tanaya Ghosh
Department of Medical Biotechnology, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.
Prasenjit Mitra
Department of Biochemistry, Sikkim Manipal University, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
Chandan Sarkar
Department of Biochemistry, Calcutta Medical College, Kolkata, West Bengal, India.
Sumanta Gupta
Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430 Siliguri,West Bengal, India.
Basudeb Basu
Department of Chemistry, University of North Bengal, Raja Rammohanpur 734430 Siliguri,West Bengal, India.
Keywords
Murrya koenigii (Linn.) Spreng Wettst ,Anti thiamine effect ,Seasonal variation ,
Abstract
A compound was isolated from Murrya koenigii (Linn.) Spreng Wettst by solvent extraction, acid hydrolysis, chromatography followed by crystallization. The compound could exert anti-ulcer activity against ethanol induced gastric ulcer and cysteamine induced duodenal ulcer in albino rats. Infra-red spectroscopy, mass spectroscopy and nuclear magnetic resonance studies revealed that the isolated compound was chemically 1,3,5-trihydroxy-7-methylanthracene-9,10-dione
Volume / Issue / Year
6 , 1 , 2016
Starting Page No / Endling Page No
29 - 35